In science, we not only try to show correlations between things, but we also try to say something about the underlying cause and what its effect is (causation). In most cases, we can only investigate correlations. It is thus important to know how causation works.
Up to 30% of people with depression do not adequately respond to our current treatments. This is a tremendous problem given the detrimental effects of depression on a person’s well-being and their environment. In the past years, Esketamine—a new drug for depression—has emerged, but is it the solution we have been waiting for?
(Social) science needs participants, whether we like it or not. Without participants there is no data, and without data there is no knowledge. The reliability of our findings is inseparable from the identity of our participants and how we are able to motivate them.