Alzheimer’s disease: too much work for microglia

This post is also available in Dutch.

Alzheimer’s disease is a well-known degenerative disease. Or let’s say, we generally know that it’s affecting and degrading memory. But why and how? Let’s have a visual explanation.

Authors: Adeline Lucchesi  – Roselyne Chauvin

Illustrations – Roselyne Chauvin

Review: Christophe Rodo – Jessica Massonnié – Lara TodorovaMarisha ManaovaJeroen Van Baar

References:

– Michaud, J.-P., and Rivest, S. (2015). Anti-inflammatory Signaling in Microglia Exacerbates Alzheimer’s Disease-Related Pathology. Neuron

– Wang, J., et al (2015). Apolipoprotein E ε4 modulates functional brain connectome in Alzheimer’s disease. Hum. Brain Mapp

– Vieira, M.N.N., and Beckman, D. (2017). Training Microglia to Resist Alzheimer’s Disease. J. Neurosci. 37, 477–479.

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